Fred Eshelman, who became wealthy developing medications, donated $100 million to the pharmacy school at the University of North Caroline at Chapel Hill last week, according to The Chronicle of Philanthropy.

So far this year, 15 other donors have contributed $100 million or more to favored causes, The Chronicle reported.

According to its tally of gifts made by early December in 2013 and 2014, contributions of $50 million or more increased by more than $800 million.

This included nearly $5 billion in donations of $50 million or more.

Bigger gifts rather than more of them accounted for the increased dollar figure, The Chronicle said, as donations of $50 million or more were static year on year.

Following are the 15 biggest gifts currently listed on The Chronicle’s database of all gifts of more than $100 million this year:

Marc Benioff, Chairman and CEO of Salesforce.com. (Photo: AP)

15. (tie) Frederic Hamilton

$100 million

Donor’s source of wealth: Investments, oil

Recipient: Denver Art Museum (Colorado)

Cause: Arts

Gift type: Estimated noncash

15. (tie) Marc R. (pictured) and Lynne Benioff

$100 million

Donor: Marc R. and Lynne Benioff

Donor’s source of wealth: Technology

Recipient: University of California at San Francisco Benioff Children’s Hospital

Cause: Health

Gift type: Pledge

15. (tie) $100 million

Donor: Anonymous

Recipient: Dartmouth College (New Hampshire)

Cause: Colleges and universities

Gift type: Gift challenge

Henry and Marie-Josee Kravis. (Photo: AP)

15. (tie) Henry R. and Marie-Josée Kravis (pictured)

$100 million

Donor’s source of wealth: Finance

Recipient: Memorial Sloan-Kettering Cancer Center (New York)

Cause: Health

15. (tie) $100 million

Donor: Dennis and Carol Troesh

Donor’s source of wealth: Industry

Recipient: Loma Linda University Health (California)

Cause: Health

Gift type: Pledge

15. (tie) $100 million

Donor: Anonymous

Recipient: Oregon Health & Science University Foundation

Cause: Colleges and universities

Gift type: Pledge

T. Denny Sanford with a patient at Rady Children's Hospital. (Photo: AP)

9. Ernest Rady

$120 million

Donor: Ernest Rady

Donor’s source of wealth: Finance, real estate

Recipient: Rady Children’s Hospital Foundation (California)

Cause: Health

Gift type: Pledge

8. T. Denny Sanford (pictured)

$125 million

Donor: T. Denny Sanford

Donor’s source of wealth: Finance

Recipient: Sanford Health (Sioux Falls, S.D.)

Cause: Health

Gift type: Pledge

7. Kenneth C. Griffin

$150 million

Donor’s source of wealth: Finance

Recipient: Harvard University (Massachusetts)

Cause: Colleges and universities

Nicholas Woodman, founder and CEO of GoPro. (Photo: AP)

6. Anonymous

$275 million

Recipient: Sanford-Burnham Medical Research Institute (California)

Cause: Medical research

Gift type: Pledge

5. Morningside Foundation (Gerald and Ronald Chan)

$350 million

Donor’s source of wealth: Family wealth, finance, investments

Recipient: Harvard School of Public Health (Massachusetts)

Cause: Colleges and universities

4. Nicholas (pictured) and Jill Woodman

$500 million

Donor’s source of wealth: Technology

Recipient: Silicon Valley Community Foundation (Mountain View, Calif.)

Cause: Community foundations

Jerry Perenchio, Former chairman and CEO of Univision Communications Inc. (Photo: AP)

3. (tie) David H. Murdock

$500 million

Donor’s source of wealth: Food and beverage, real estate

Recipient: David H. Murdock Research Institute (North Carolina)

Cause: Science

Gift type: Estimated pledge

3. (tie) Jerry Perenchio (pictured)

$500 million

Donor’s source of wealth: Media and entertainment

Recipient: Los Angeles County Museum of Art (California)

Cause: Arts

Gift type: Pledge

1. Stanley Family Foundation (Theodore Stanley, Founder, MBI)

$650 million

Donor’s source of wealth: Marketing

Recipient: Broad Institute (Massachusetts)

Cause: Health

Gift type: Pledge

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